Edzard Schwedhelm Selected Research

Hypercholesterolemia

2/2008	Simultaneous assessment of endothelial function, nitric oxide synthase activity, nitric oxide-mediated signaling, and oxidative stress in individuals with and without hypercholesterolemia.
3/2007	Asymmetrical dimethylarginine (ADMA) and coronary endothelial function in patients with coronary artery disease and mild hypercholesterolemia.
12/2005	Elevation of asymmetrical dimethylarginine (ADMA) and coronary artery disease in men with erectile dysfunction.
8/2004	Hypercholesterolemia impairs basal nitric oxide synthase turnover rate: a study investigating the conversion of L-[guanidino-(15)N(2)]-arginine to (15)N-labeled nitrate by gas chromatography--mass spectrometry.
2/2004	Urinary 8-iso-prostaglandin F2alpha as a risk marker in patients with coronary heart disease: a matched case-control study.
1/2004	Determination of asymmetric dimethylarginine (ADMA) using a novel ELISA assay.

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Edzard Schwedhelm Research Topics

Disease

44	Cardiovascular Diseases (Cardiovascular Disease) 11/2023 - 12/2003
20	Hypertension (High Blood Pressure) 11/2023 - 01/2004
17	Atherosclerosis 11/2023 - 01/2004
15	Stroke (Strokes) 07/2023 - 03/2009
14	Heart Failure 09/2023 - 01/2004
11	Myocardial Infarction 07/2023 - 04/2008
10	Atrial Fibrillation 04/2024 - 01/2016
9	Ischemic Stroke 07/2023 - 10/2009
9	Coronary Artery Disease (Coronary Atherosclerosis) 04/2021 - 07/2004
8	Inflammation (Inflammations) 11/2023 - 07/2004
8	Sepsis (Septicemia) 11/2023 - 10/2015
8	Diabetes Mellitus 10/2022 - 01/2004
6	Insulin Resistance 11/2023 - 09/2006
6	Chronic Renal Insufficiency 10/2022 - 05/2009
6	Hypercholesterolemia 02/2008 - 01/2004
5	Fibrosis (Cirrhosis) 12/2022 - 11/2005
5	Metabolic Syndrome (Dysmetabolic Syndrome X) 10/2022 - 11/2007
5	Vascular Diseases (Vascular Disease) 01/2022 - 04/2008
5	Essential Hypertension 01/2020 - 09/2006
5	Coronary Disease (Coronary Heart Disease) 03/2013 - 07/2006
4	Reperfusion Injury 12/2023 - 09/2009
4	Disease Progression 09/2023 - 01/2021
4	Brain Ischemia (Cerebral Ischemia) 01/2022 - 09/2009
4	Parkinson Disease (Parkinson's Disease) 01/2021 - 10/2020
4	Type 2 Diabetes Mellitus (MODY) 01/2014 - 07/2005
3	Pre-Eclampsia (Preeclampsia) 08/2023 - 02/2004
3	Neoplasms (Cancer) 01/2021 - 10/2009
3	Pulmonary Arterial Hypertension 01/2019 - 10/2012
3	Body Weight (Weight, Body) 09/2015 - 08/2004
2	Ischemia 12/2023 - 08/2022
2	Critical Illness (Critically Ill) 11/2023 - 12/2009
2	Transient Ischemic Attack 07/2023 - 03/2009
2	Cerebrovascular Disorders (Cerebrovascular Occlusion) 06/2022 - 03/2020
2	Atherosclerotic Plaque (Atheroma) 01/2022 - 01/2015
2	Osteoporosis 01/2021 - 01/2018
2	Muscular Diseases (Myopathy) 07/2020 - 01/2020
2	Cardiomegaly (Heart Hypertrophy) 01/2020 - 01/2016
2	Septic Shock (Toxic Shock Syndrome) 01/2019 - 01/2017
2	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy) 01/2019 - 01/2016
2	Cardiomyopathies (Cardiomyopathy) 01/2018 - 12/2012
2	Hyperlipidemias (Hyperlipidemia) 12/2017 - 09/2006
2	Peripheral Arterial Occlusive Disease 1 09/2015 - 01/2003
2	Overweight 09/2015 - 02/2011
2	Kidney Diseases (Kidney Disease) 08/2014 - 05/2011
2	Albuminuria 10/2012 - 10/2008
2	Alzheimer Disease (Alzheimer's Disease) 01/2012 - 01/2008
2	Chronic Kidney Failure (Chronic Renal Failure) 12/2009 - 05/2009
2	Proteinuria 10/2008 - 07/2005
2	Erectile Dysfunction 12/2005 - 08/2002

Drug/Important Bio-Agent (IBA)

33	Arginine (L-Arginine)FDA Link 11/2023 - 01/2003
31	HomoarginineIBA 09/2023 - 09/2013
28	N,N-dimethylarginine (asymmetric dimethylarginine)IBA 01/2021 - 02/2004
26	Biomarkers (Surrogate Marker)IBA 08/2023 - 07/2006
18	Nitric Oxide (Nitrogen Monoxide)FDA Link 11/2023 - 08/2002
16	symmetric dimethylarginineIBA 11/2023 - 02/2010
14	dimethylarginineIBA 08/2023 - 08/2002
13	Nitric Oxide Synthase (NO Synthase)IBA 01/2021 - 08/2002
9	EnzymesIBA 09/2023 - 12/2009
8	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 08/2022 - 10/2015
7	Amino Acids FDA Link 11/2023 - 01/2015
7	LipidsIBA 01/2022 - 12/2014
6	glycine amidinotransferase (arginine-glycine amidinotransferase)IBA 01/2022 - 09/2013
6	Telmisartan (Micardis)FDA Link 10/2008 - 07/2005
5	Angiotensin IIIBA 11/2023 - 05/2009
5	CreatineIBA 02/2023 - 03/2020
5	IsoprostanesIBA 01/2022 - 12/2003
4	HDL CholesterolIBA 01/2022 - 12/2005
4	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 07/2020 - 07/2009
4	C-Reactive ProteinIBA 02/2011 - 07/2004
4	Nisoldipine FDA Link 10/2007 - 09/2006
3	Glucose (Dextrose)FDA LinkGeneric 11/2023 - 12/2005
3	Prostaglandin H2 Thromboxane A2 ReceptorsIBA 11/2023 - 01/2022
3	F2-Isoprostanes (F2 Isoprostanes)IBA 01/2022 - 05/2006
3	Proteins (Proteins, Gene)FDA Link 03/2021 - 09/2015
3	HDL LipoproteinsIBA 01/2019 - 02/2011
3	Clopidogrel (Plavix)FDA Link 12/2017 - 07/2006
3	dimethylargininaseIBA 01/2012 - 12/2009
3	Angiotensin Receptor AntagonistsIBA 10/2008 - 07/2005
3	Antihypertensive Agents (Antihypertensives)IBA 10/2008 - 09/2006
3	Calcium Channel Blockers (Blockers, Calcium Channel)IBA 10/2007 - 09/2006
3	8-epi-prostaglandin F2alphaIBA 05/2006 - 02/2004
2	CollagenIBA 12/2022 - 11/2005
2	Lipoproteins (Lipoprotein)IBA 01/2022 - 01/2019
2	omega-Chloroacetophenone (Mace)IBA 01/2022 - 04/2021
2	Simvastatin (Zocor)FDA LinkGeneric 07/2020 - 01/2020
2	Ranolazine FDA Link 01/2019 - 01/2016
2	NitratesIBA 11/2017 - 08/2004
2	Insulin (Novolin)FDA Link 09/2015 - 09/2006
2	Oxidants (Oxidizing Agents)IBA 07/2014 - 07/2006
2	LDL Lipoproteins (beta Lipoproteins)IBA 02/2011 - 07/2004
2	CholesterolIBA 07/2009 - 08/2004
2	Valsartan (Vals)FDA Link 10/2008 - 07/2005
2	CreatinineIBA 10/2008 - 08/2007
2	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 04/2008 - 07/2006
1	dapagliflozinIBA 04/2024
1	Colloids (Colloid)IBA 12/2023
1	Crystalloid SolutionsIBA 12/2023
1	Starch (Cornstarch)IBA 12/2023

Therapy/Procedure

5	Therapeutics 12/2023 - 07/2006
2	Patient Readmission 12/2021 - 02/2012